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          當前位置:首頁資料下載Wnt1抗原,信號通路Wnt1抗原

          Wnt1抗原,信號通路Wnt1抗原

          發布時間:2024/11/10點擊次數:106

          Recombinant human Wnt1   

          wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.    

          濃度:1mg/ ml

          來源:Recombinant Human

          純度:95% SDS-PAGE

          表達系統:Escherichia coli

          標簽:His tag   

          蛋白長度:Full length protein

          內毒素水平:<1.000 Eu/µg

          純化方法:HPLC

          應用:SDS-PAGEWestern blot,ELISA

          Biological activity,immunology research

          保存:-20

          保質期:1

          TThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.



          產品名稱:Rabbit Anti-Wnt1 antibody

          Rabbit Anti-Wnt1 

          別名:wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.               

          來源:Rabbit

          克隆類型:Polyclonal

          濃度:1mg/ml

          亞型:IgG

          反應:Human,Mouse,Rat (predicted: Cow,Chicken,Horse)

          應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

                 IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

          理論分子量:39kDa

          免疫原:KLH conjugated synthetic peptide derived from human Wnt1

          保存:-20
          保質期:1

           

           

          產品名稱:Anti-Wnt1 antibody

          Mouse Anti-Wnt1

          別名:wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.                   

          來源:Mouse

          克隆類型:Monoclonal

          濃度:1mg/ml

          亞型:IgG

          反應:Human

          應用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

                 IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

          反應:  Human

          理論分子量:39kDa

          免疫原:KLH conjugated synthetic peptide derived from human Wnt1

          保存:-20
          保質期:1

          The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.


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